Databasing

...without the use of a database plugin.

I want to know if it is possible to use MySQL or some other SQL databasing system (SQLyog, SQLite, etc.) with the PerlScript portion of MUSHclient.

Yes. You can do anything that perlscript can do.

All the database plugin does is use the java/database connector, there are similar ones in most other languages.

Personally, I don't know exactly how to do it, however I'm sure googling perlscript SQL should return whatever you need.